PhD in Biology. Founder of the NGO “Institute of Good Food of Ukraine”. Senior Lecture, Department of Biotechnology and Radiology, Stepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies of Lviv, Ukraine.

Biotechnology specialist with hands-on experience in molecular biology, genetic engineering, and immunobiotechnology. Completed advanced training programs, professional internships, and international summer schools. Skilled in laboratory techniques and bioinformatics tools. Committed to scientific research, interdisciplinary collaboration, and continuous development.

Professional Experience

2023-Present

Senior Lecture, Department of Biotechnology and Radiology, Stepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies of Lviv, Ukraine.

2021-2023

Teaching Assistant, Department of Biotechnology and Radiology, Stepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies of Lviv, Ukraine.

2018-2021

Research Assistant, Department of Immunology, Centre for Innovative Research in Natural and Medical Sciences, Medical Faculty, University Of Rzeszow, Poland.

2016-2018

Senior Engineer, Department of Regulation of Cell Proliferation and Apoptosis, Institute of Cell Biology, NAS of Ukraine, Lviv, Ukraine.

2011-2012

Engineer, Department of Molecular Genetics and Biotechnology, Institute of Cell Biology, NAS of Ukraine, Lviv, Ukraine.

Education

PhD in Biology

Graduated: 2018

– Post-graduate student (2012-2016), Department of Immunology, Institute of Animal Biology NAAS of Ukraine, Lviv, Ukraine.

– Thesis title: “Wnt signaling pathway inhibition by interleukin 6 and its role in the development and progression of rheumatoid arthritis” Student (2007-2012), Department of Biochemistry, Biological Faculty, Ivan Franko Lviv National University, Ukraine.

Master Level Specialist in Science in Biochemistry

 Graduated: 2012

– Thisis title: “Biochemical properties of recombinant strains of the methylotrophic yeasts Hansenula polymorpha with deletions of homologues of transport protein HGTIP/Opt1p/Gsh11p”.

Membership

– The Ukrainian Biochemical Society (full member of the Federation of European Biochemical Societies, FEBS).

– Good Food Institute Ukraine.

Languages

– Ukrainian (native)

– English (upper-intermediate)

– Polish (intermediate)

Certification

– Professional Internship, State Service of Ukraine on Food Safety and Consumer Protection & SSRCIVPFA, Lviv (Feb 12 – Mar 22, 2024), 6 ECTS (180 hrs).

– Comprehensive Training Program for Biomethane Production in Ukraine USAID Energy Security Project & Bioenergy Association of Ukraine (UABIO) (Jan 14, 2024), 20 hrs.

– XIX International Summer School for Young Scientists “Molecular Biology, Biotechnology, and Biomedicine” Odesa, Ukraine (Jul 8-19, 2024) (Equivalent to 3 ECTS, 90 hrs).

– Laboratory Internship, ISO/IEC 17025:2019 accredited lab, SSRCIVPFA (Jan 20 – 24, 2025), 1.3 ECTS (40 hrs).

Awards & Grants

– 2022 Bursary International Scholarship for Young Rheumatologist, 42nd KCR Annual Scientific Meeting and the 16th International Symposium, Seoul Dragon City, Seoul, Korea

– 2017 Bursary FEBS Collaborative and Experimental Scholarship for Central & Eastern Europe «Wnt signaling pathway inhibition in development and progression of inflammatory arthritis», NovemberDecember, Rzeszow, Poland.

– 2016 Bursary 41st FEBS Congress, Kusadasi, Turkey.

– 2014 Grant Young biomedical researchers Grant, 18th annual competition of the West-Ukrainian BioMedical Research Center (WUBMRC), Lviv, Ukraine.

List of Publications

• h-index -4 (Google Scholar) • h-index -3 (Scopus)

1. Rudenko, O.P.; Malysheva, K.V.; Kurtiak, B.M.; Pundiak, T.O.; Romanovych, M.S. Rabies in Ukraine: Pathogenesis, Diagnostics, and Epidemiological Trends in the Lviv Region. One Health J. 2025, 3, 5—24.

2. Soboleva, A.l.; Shemedyuk, N.P.; Muzyka, V.P.; Rudenko, O.P.; Malysheva, K.V. Encapsulation of Hydrophobic Bioactive Compounds in Yeast Cells: Mechanisms, Challenges, and Applications in Biotechnology. Sci. Messenger LNUVMB Ser. Food Technol. 2024, 26(102).

3. Tolok, 0.; Malysheva, K. Regulation of Proliferative Potential: Insights into Key Signaling Cascades and Telomerase Functions. Sci. Messenger LNUVMB Ser. Food Technol. 2024, 26(102), 85-90.

4. Makovei, R.; Shemedyuk, N.; Malysheva, 1<.; Dvylyuk, 1.; Chokhan, M. Development of a Bioinformatics Tool for Identifying Members of the Apis mellifera Gut Microbiome. Sci. Messenger LNUVMB Ser. Food Technol. 2024, 26(102), 98-102.

5. Kwasniak, K.; Czarnik-Kwaéniak, J.; Malysheva, K.; Pogoda, K.; Korchynskyi, 0.; Rybojad, P.; Karczmarek-Borowska, B.; Tabarkiewcz, J. LncCDH5-3:3 Regulates Apoptosis, Proliferation and Aggressiveness in Human Lung Cancer Cells. Cells 2022, 11, 378. (IF: 7.66; SJR-QI)

6. Malysheva, 1<.; Kwasniak, K.; Gnilitskyi, Y.; Barylyak, A.; Zinchenko, V.; Fahmi, A.; Korchynskyi, 0.; Bobitski, Y. Functionalization of Polycaprolactone Electrospun Osteoplastic Scaffolds with Fluorapatite and Hydroxyapatite Nanoparticles: Biocompatibility Comparison of Human versus Mouse Mesenchymal Stem Cells. Materials 2021, 14(6), 1333. (IF: 3.62; SJR-Q2)

7. Kucinska-Lipka, J.; Gubanska, 1.; Korchynskyi, 0.; Malysheva, 1<.; Kostrzewa, M.; Wtodarczyk, D.; Karczewski, J.; Janik, H. The Influence of Calcium Glycerophosphate (GPCa) Modifier on Physicochemical, Mechanical, and Biological Performance of Polyurethanes Applicable as Biomaterials for Bone Tissue Scaffolds Fabrication. Polymers 2017, 9(8), 329. (IF: 3.364)

8. Malysheva, K.; Pavlenko, 0.; Stoika, R.; Korchynskyi, O. ShRNA-Mediated Knockdown of Pituitary Tumor Transforming Gene 1 (PTTGI): Optimization of the Effect and Targeting of Early Osteoblast Differentiation in Murine Mesenchymal Stem Cells. Anim. Biol. 2017, 19(2), 70-78.

9. Malysheva, K.; Finiuk, N.; Pavlenko, 0.; Havrylyuk, D.; Lesyk, R.; Stoika, R.; Korchynskyi, O. 4-Thiazolidinone-Based Derivatives Rescue TN Fa-lnhibited Osteoblast Differentiation in Mouse Mesenchymal Precursor Cells. Ukr. Biochem. J. 2017, 89(Special Issue), 112-123.

10. Malysheva, K.; Spasyuk, 1.; Pavlenko, 0.; Stoika, R.; Korchynskyi, O. Generation of Optimized Preparations of Bone Morphogenetic Proteins for Bone Regeneration. Ukr. Biochem. J. 2016, 88(6), 87-97.

11. Malysheva, K.; de Rooij, M.; Löwik, C.; Baeten, D.; Rose-John, S.; Stoika, R.; Korchynskyi, O. Interleukin 6/Wnt Signaling Interaction in Rheumatoid Arthritis: Interleukin 6 Inhibits Wnt Signaling in Synovial Fibroblasts and Osteoblasts. Croat. Med. J. 2016, 57(2), 89-98. (IF: 1.619)

12. Krupak, V.; Malysheva, K.; Pavlenko, 0.; Shafranska, G.; de Rooij, K.; Löwik, C.; Stoika, R.; Korchynskyi, O. The PTTGI Is a Novel Inhibitor of Osteogenic Differentiation of Mouse Mesenchymal Stem Cells. Anim. Biol. 2016, 18(1), 6168.

13. Malysheva, K.; de Rooij, K.; Löwik, C.; Baeten, D.; Stoika, R.; Korchynskyi, O. ShRNA-Mediated Knockdown of Interleukin 6 Expression Rescues Tumor Necrosis Factor a-Inhibited Osteogenesis in Mouse Mesenchymal Precursor Cells. Studia Biologica 2015, 9, 5-14.